The most commonly reported adverse reactions were hypersensitivity reactions (e.g., rash, urticaria), edema-related reactions (e.g., arthralgia, extremity pain, peripheral edema, and carpal tunnel syndrome), hyperglycemia, and injection site reactions (injection site erythema, pruritus, pain, urticaria, irritation, swelling, and hemorrhage)
Basso L, McCollum PT, Darling MR, Tocchi A, Tanner WA
Overall, with appropriate patient selection, dosing, and monitoring (periodic IGF-1 testing, glucose monitoring in at-risk individuals, clinical assessment), Sermorelin appears to have a favorable benefit-to-risk profile for addressing GH deficiency or age-related GH decline
Impact of alcohol and cigarette smoking consumption in male fertility potential: Looks at lipid peroxidation, enzymatic antioxidant activities and sperm DNA damage